Rikky1 When I started it over a month ago I took the tincture first and did the minimal dropslike 10..then I quickly moved to 1/4 teaspoon..but then I switched to 5 herb capsules for convenience. The book says it should contain 500mg of the Polygonum cuspidatum, but the bottle says 200mg. In 70 to 80 percent of the infected persons, a rash occurs at the site of bite after a delay of about 3 to 30 days. Activated charcoal is a great binder, but it can be constipating. we are planning to do doxycycline for 4 weeks with herbal on side (starting 1 drop and increasing) I so appreciate your response. The Buhner/Rawls combination helps about 60-65 percent of the time in my clinical observations. Wow you guys are diehards with how much you can tolerate I'm jealous. Before you start any treatment, consult a certified lyme expert! 1st day: 1 drop per day. Therefore, it is worth considering the addition of these natural substances with the use of doxycycline for a more comprehensive and effective antimicrobial action. In my practice, I offer two persister-oriented regimens for those that have failed years of regular antibiotics. There are four protocols for Lyme that I have had good success with. I was only taking 1 200mg a day and I started taking 400 3x a day and I am having a very bad neuro herx that I can't stop with my normal methods. Its active constituent ARTEMISININ is famous Was recognized in 2015 with a Nobel Prize from its role in treating malaria! There is a Babesia Buhner protocol .you know that right? Could time-restricted eating cause fertility problems? http://aspire.care/featured/overview-of-lyme-tick-borne-illness/ Dr. Wells has focused her practice on pediatric primary care and consultative care for Autism Spectrum Disorder (ASD), PANS/PANDAS, other neurodevelopmental disorders, and various chronic illnesses. Some studies have suggested that resveratrol may have anticancer properties, and may protect heart and brain health. Cameron DJ, Johnson LB, Maloney EL. It is primarily useful for cancer treatment because of its antioxidant nature but besides its conventional use it can also be used as an efficient measure against Lyme arthritis. Can you help me? 2008;5:40. doi:10.1186/1742-2094-5-40(, Pothineni VR, Wagh D, Babar MM, et al. That was my max. Inflammation can occur through a number of different pathways in the body but the root of this plant is specific for the exact pathways that the Lyme bacteria initiate. Ill send the freshest remedies and contents straight to your inbox. Did you or someone in your life experience Lyme disease? Besides killing Lyme bacteria, it can also be employed to treat cardiovascular diseases, cancer, to prevent aging, for antimicrobial uses, weight loss, etc. Dr. Ross is licensed to practice medicine in Washington State (License: MD00033296) where he has treated thousands of Lyme disease patients inhis Seattle practice. Japanese Knotweed- 7000mg per day = 10 capsules Cat's Claw - 7000 mg per day = 10 capsules Eleutherococcus - 4200 mg per day = 6 capsules Note- I took a 2 week break every 60 days I began with one herb at a time. Hence, it is very much desirable to eliminate its symptoms and effects as soon as they become visible. The following are four general rules I use to develop a Lyme disease antibiotic regimen: Be aware the doses I provide below are for adults. They will depend on your present health condition and the intensity of infection caused by the Lyme disease. Please share how long any of the herbal protocols should ne used for? By Sebastian Kettley 17:00, Fri, Feb . Japanese knotweed. Working with a knowledgeable naturopath or md to use herbs and diet is suggested. Study 1: Cooperation of Doxycycline with Phytochemicals and Micronutrients Against Active and Persistent Forms of Borrelia, Source: Goc, Anna & Niedzwiecki, Aleksandra & Rath, Matthias. Research first published in 2015 shows that Lyme has two different growth states. In addition, theyre safer for long-term use, so we feel very comfortable using it for longer periods of time. Based on Horowitz experiments and my use of the medication with my patients, I find improvements of 20 percent or so in those that can tolerate the treatment. I use hooftinder polypore in this which also is good in Lyme treatment. Here is my Question: Do you recommend me to do blood test for coinfections, as well? Note: I work with the following anti-cyst agents based on the mechanism by which these antibiotics work and some scientific experiments. The two plant extracts also killed entire microcolonies of the bacterium that causes Lyme disease. It activates Sirtuin Genes, imitating the functioning of a calorie-restricted diet. but they have all led to dead-ends. Lyme disease caused by such bacteria is a multi-system inflammatory disease that starts itself by affecting the skin first, and then spreads to central nervous system, joints, etc. When we were beginning the herbal bartonella protocol and I was messing around with dosages of the other herbs, I found that 1 double dose (ie 4 grams) of either the powdered japanese knotweed herb or the tincture was enough to bring her out of an emotional herx (ie rage ). It's possibly a backslide. Not surprisingly they are both greatly feared and dreaded. Follow the steps in Cant Get Better? It has been identified in high concentrations as a strong flavonoid, at the roots of the plant. Both protocols are appropriate for chronic Lyme, have the same dosage, and can be used interchangeably. These persistershibernating phase germsignore regular standard antibiotics we traditionally used to treat Lyme. EGCG is the active constituent in green tea, a potent antioxidant. 2020;9(9):633. doi:10.3390/antibiotics9090633(, Sapi E, Kaur N, Anyanwu S, et al. I do recommend diffusing essential oils in the air or apply a dropper or two topically. Japanese knotweed is a traditional medicine in India and China that contains the polyphenol resveratrol. Therefore, the plan that follows is notand cannot bea complete or comprehensive guide. Front. Japanese knotweed (pictured above) is one of the two plants whose active compounds appear to be highly effective against the bacterium that causes Lyme disease. What can I say, I'm jealousI'm actually having this one muscle tested on Thursday because I don't seem to tolerate it well. Even a year or more into treatment, when a person is feeling better, these steps are essential to speed recovery by supporting the immune system. Although the current recommended Lyme antibiotic treatment is effective for the majority of Lyme disease patients, about 10-20% of patients continue to suffer from persisting symptoms. These are doxycycline, cefuroxime, and amoxicillin. Inside of cells, Lyme may live in cave-like structures called vacuoles. http://primitiveskills.com Mike DiMauro shares how he has treated and continues to address the prevention of Lyme Disease using Japanese Knotweed. The researchers also tested some other substances that anecdotal evidence had indicated might be effective against Lyme disease. I usually put Cats Claw in my protocols for Lyme, specifically Borrelia. I also start this one with a low dose, meaning one drop and increase as tolerated based on theyre weight. When tested in melanocytes (melanin producting cells under the skin), a component in Polygonum called Piceid is able to inhibit tyrosinase activity in a dose-dependent manner [7] and may act . These are known as persister cells. At the beginning of treatment for someone with chronic Lyme, it is difficult to predict what the length and degree of recovery will be. Here is a list of prescription medications shown in human experiments to help with persister Lyme. Tetracyclines and macrolides both block protein production by binding to the protein production apparatus in germs called ribosomes. I recently stopped antibiotics and upped my JK. Brilliant, informative article. Quantity Following is a rough list for required dosages of Japanese Knotweed:-, For a 150 pounds weighing adult 1 teaspoon for 3 times in a day, For a 100 pounds weighing adult 2/3 teaspoon for 3 times in a day, For 60 pounds weighing child 1/3 teaspoons for 3 times in a day (tincture is more desirable and effective), For a 30 pounds weighing child 1/5 teaspoons for 3 times in a day (tincture may act as a better option). My first hand experience with chronic Lyme and several co-infections has been arduous, very financially draining and more often than not severely painful. A Miracle Antibiotic? Intensive treatment. To aid with alkalization, you can consider Alka Seltzer gold. It is a member of group of plant compounds known by the name of polyphenols. The reason I like Buhner is that it uses single herbals, meaning that theres not a combination of a tincture. Im wary of stopping before the protocol has reached its maximum effect. Its active constituent is Artemisia. But I also include in protocols for PANS patients in which viruses are at play. It is considered to be the most effective herbal way to lower, or even eliminate Lyme disease and its symptoms. The thought is that those who are more alkaline, so less acidic, tend to have less extreme herxheimer reactions or die-off reactions. It's known as Hu Zhang in Traditional. Add every day 3 x 1 drop, till 3 x 15 drops per day is reached. They compared the results with those of two of the traditional drugs used against Lyme disease: doxycycline and cefuroxime. https://www.ilads.org/patient-care/provider-search/, Hi I live in Australia and like so of the people with Lyme disease, my son has struggled for over 25, years, physically, financially, and mentally. For more information about this, see When Will I Start to Feel Better? Each of these herbal medicine options is shown in lab experiments to treat growing and persister phases of Lyme. Study 2: Natural and Botanical Medicines for Activity Against Growing and Non-growing Forms of B. burgdorferi, Source: Feng Jie, Leone Jacob, Schweig Sunjya, Zhang Ying Evaluation of Natural and Botanical Medicines for Activity Against Growing and Non-growing Forms of B. burgdorferi. hi. Teasel can be used for Lyme and I have had great success with. You can even send a message about the hiccup, that would be awesome! Polygonum Cuspidatum) is a root in the form of ground tincture or tablets. Once I got to the full dosage for my weight I started the next herb. Tox-ease-GL, I sometimes use for herx reactions. This tincture is now available on Amazon, here. I use pretty often for my mycoplasma kiddos with pans or just active mycoplasma in general. It is time to stop a full treatment when someone is either symptom-free for two months or the improvements have plateaued for four months after adjusting the regimen. The many herbal actions Buhner lists for Japanese knotweed include antibacterial, antiviral, anti-spirochetal, immunostimulant, anti-inflammatory, central nervous system relaxant, brain and spinal cord protectant, anti-carcinogenic, vasodilator, cardioprotective, antithrombotic, hemostatic and astringent. Aspire. This bacteria is very smart. I hope you can see a lyme literate doctor. Antibiotics that work on germs inside and outside of cells include the tetracyclines, macrolides, rifamycins, and azoles. What remains are body temperature dysregulation (get hot/sweaty and a mild fever), shortness of breath and leg cramps when I walk up stairs or a mild incline, headaches, nausea/GERD, pain on the bottom of my feet, weight loss, pain flares, and the consistent low mood. Chinese Skullcap is usually in my starting lineup for treatments for Lyme disease because of its anti-inflammatory and antimicrobial activity, but it also has neuroprotective, antioxidant, and anti-excitatory properties. When the spirochete is in its active form, it can divide and reproduce; this is when antibiotics are the most effective in killing them off. It supports the innate immune function to react to the infection caused by the Lyme disease. Any labs in Europe you can recommend? This herbal is a potent anti-parasitic. Evidence assessments and guidelines recommendations in Lyme disease: The clinical management of known tick bites, erythema migrans rashes and persistent disease. So I would look at the list and join a bartonella/lyme facebook group and ask for recommendations too. Some of it sounds like addisons You got me curious! Infect Microb Dis. Longer-term use could be months or years, depending on the severity of the illness. It is one of my go-to herbals for Babesia, a common co-infection. The most important health benefits of Japanese knotweed may include its ability to prevent and treat cognitive disorders, improve heart health, lower your risk of cancer, reduce gastrointestinal distress, lower blood pressure, maintain proper insulin levels, and many other unique benefits. This herbal comes in cat, dog, human and horse doses. Be careful when shopping because you want to make sure you are getting the correct one. Theres a variable duration of a herx reaction and onset can often happen within hours. Type 2 diabetes and cognitive decline: Is Tai chi more effective than walking? Important compound in Japanese Knotweed. This is often due to a Herxheimer die-off reaction. What I like about Byron Whites formulations is that they have an energetic component and that energetic component works against the specific germ you are trying to target. More detail on Chinese Skullcap is included further on in this article. Fortunately, intracellular antibiotics also reach Lyme outside of cells, too. Take the powder of Japanese knotweed one teaspoon (or it is also recommended for tablespoon), that mixed with juice 3 for times a day probably will be effective to heal lyme's disease. Published : May 21, 2020 Thank you, We have a list of practitioners suggested by parents, caregivers and patients on the website. Infect Drug Resist. I tend to start that way with a lot of our kids, especially with PANS/PANDAS or autism, as they tend to be very sensitive. Antibiotics (Basel). Perhaps Japanese Knotweed works for Lyme because in some ways they have a similar temperament. Townsend Letter. Mar 18, 2013 | dosage info, Herbs, japanese knotweed, The Basics | 26 comments. Japanese knotweed may be more effective than antibiotics at tackling Lyme disease, new study has found. In other preclinical studies, it has been found to have anti-tumor and anti-inflammatory effects and protect the nervous system and heart. 2019;8(2):50. doi:10.3390/antibiotics8020050(, Liegner KB. 2016;59(8):46164624. Is the ketogenic diet right for autoimmune conditions? The above, including the herbs and sources, are . Subscribe to receive our FREE pdf download book: How to Successfully Treat Lyme: Key Info before You Treat or Treat Again & The Ross Lyme Support Protocol; health tips; updates; special offers; and more. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. We are not doctors and treatment must be individualized. In the book, you recommend Japanese knotweed. Since azithromycin is not as effective as other macrolides like clarithromycin, hydroxychloroquine is used to increase the effectiveness. Its been shown to reduce short-term memory impairment when its combined with IV ceftriaxone in patients with Lyme disease. Resveratrol can also increase lifespan by 30 percent. They appear to kill intracellular and extracellular Lyme, too, based on the clinical benefit I see in my medical practice. They are all in glycerin form, so they taste better are more tolerated by children. The last thing I want to do is kill off bugs and have them just sit in the body to be reabsorbed, increasing inflammation by reabsorbing toxins. Further, Cryptolepis sanguinolenta and Polygonum cuspidatum (Japanese knotweed) showed strong activity against both growing B. burgdorferi (MIC=0.03%-0.06% and 0.25%-0.5% respectively) and non . Schizophrenia: Researchers say network disruptions in the brain may be a factor, Schizophrenia: How blood vessel growth in the brain may be a factor, Why adults in rural areas face higher risk of heart failure, Leftover bacteria fragments may extend symptoms of Lyme disease, These 10 essential oils can kill persistent Lyme disease. Top on the list was Cryptolepis, behind that Japanese knotweed, cat's claw, Chinese skullcap, artemisia, black walnut, Cistus incanus, which is actually more of an essential oil, Andrographis, stevia, grapefruit seed extract, and monolaurin. But in reality, the mitochondria are part of what is working to fight off the infection. In early treatment of the disease, infection and symptoms can be removed by antibiotics but delayed or inadequate treatment can result into more serious symptoms, which can be difficult to treat. This infectious disease is caused via the bite of an infected tick. What is more, the bacterium was unable to make a comeback following this treatment. Essentially what happens is that the baseline symptoms intensify. (See IV Equivalent Treatments below. Even a year or more into your treatment, these 10 steps are essential to resuscitate and support the immune system. Insect vectors such as mosquito, are also believed to act as a host to the Lyme causing bacterium. Motherwort can also increase BAX, which needs to be in a modulated balance with the BCL-2. Also, it is also anti-microbial, protects the central nervous system, clears out endotoxins, anti oxidant, and is . Before I describe herbal and prescription antibiotic approaches I find helpful treating Lyme in my Seattle practice, lets talk about terms. Lyme spirochetes and cysts can exist in growing phases and in persister phases. The researchers pitted each of these plant extracts against free-swimming (planktonic) B. burgdorferi and microcolonies of this bacterium aggregates of bacterial cells. Some people dont like the taste, but its worth considering, and you can do it up to three times a day. Today, we know it simply. Polygonum cuspidatum (Japanese knotweed) . Some lab experiments suggest that the great majority exist in the growing phase; however, prolonged use of regular antibiotics may push a greater portion of the germs into the persister phase. This is the second time I am making this point because it is very important. For Lyme's disease many recommend using from a teaspoon or more (some even recommend a tablespoon) of the powder 3 times a day mixed with juice, this is a much higher dose for Lyme's disease. 2016;3(3-4):7582. This herbal medicine is traditionally used to treat Lyme, which Stephen Buhner recommends. The plants in question were black walnut (Juglans nigra), cats claw (Uncaria tomentosa), sweet wormwood (Artemisia annua), Mediterranean rockrose (Cistus incanus), Chinese skullcap (Scutellaria baicalensis), Ghanaian quinine (Cryptolepis sanguinolenta), and Japanese knotweed (Polygonum cuspidatum). Herbals may provide relief to those in which antibiotics didnt help completely. 2020;20(1):87. doi:10.1186/s12866-020-01777-9(. Just starting taking it. Int J Biol Sci. Again, I use a lot for my PANS kids if they have parasites. This is a really nice formula that can be supportive when you start to add in different herbs. Sometimes kids really being given the option to choosing a few different scents. The antibiotic is based on a compound found in soil. Grapefruit seed extract is better tolerated than both tinidazole and metronidazole and supports killing of Lyme cysts. THE CORE BUHNER PROTOCOL FOR BARTONELLA INFECTIONS: Japanese knotweed root tincture (cytokine cascade reduction and endothelial cell protection) , 1/4-1/2 tsp 3x daily If your child didnt respond well to a combination product, we wouldnt know which herb was an issue. I did Japanese Knotweed in tincture form. Then the body responds to those biotoxins by increasing inflammatory cytokines, IL-6, IL-8, and TNF-a, and that increased inflammation causes us to have an increase in symptoms. 2nd day: 2 x 1 drop per day. Start with taking low dosages, and increase the dosages gradually, in weeks. Med., 21 February 2020. Japanese Knotweed can be used in two forms, capsule and tincture. 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Than walking alkaline, so we feel very comfortable using it for longer periods of time effectiveness! Me curious than walking working with a knowledgeable naturopath or md to use herbs diet! Herbal comes in cat, dog, human and horse doses, hydroxychloroquine is to. Before I describe herbal and prescription antibiotic approaches I find helpful treating Lyme my! Diabetes and cognitive decline: is Tai chi more effective than antibiotics at tackling Lyme disease the researchers pitted of. Air or apply a dropper or two topically, Sapi E, Kaur N, Anyanwu S et! The intensity of infection caused by the Lyme disease this herbal comes cat. Has been arduous, very financially draining and more often than not painful...